7218/10 | Tocris Bioscience 7218/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7218/10

catalog :

7218/10

quantity :

10 mg (also 50 mg)

price :

250 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7218 - PZM21 C19H27N3O2S CAS No. 1997387-43-5

product information

master code :

7218

SKU :

7218/10

product name :

PZM21

unit size :

10 mg (also 50 mg)

description :

Selective receptor agonist

target :

mu Opioid Receptor Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

361.5

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PZM21 is a selective receptor agonist (EC50 = 4.6 nM). PZM21 has been reported to exhibit bias for the Gi signaling pathway over arrestin-3. The compound exhibits 500-fold selectivity for over receptors and no detectable activity at or nociceptin receptors and a panel of 316 other GPCRs. PZM21 induces analgesia in a mouse hot plate assay, but not a tail-flick assay and exhibits no significant conditioned place preference response in in vivo assays. CNS penetrant.

top caption :

Selective receptor agonist

extended description :

Selective receptor agonist

chemical name text :

N-[(2S)-2-(Dimethylamino)-3-(4-hydroxyphenyl)propyl]-N -[(1S)-1-methyl-2-(3-thienyl)ethyl]urea

formula :

C19H27N3O2S

formula text :

C19H27N3O2S

cas num :

1997387-43-5

USD :

250 USD

product details :

Selective receptor agonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage