7195/50 | Tocris Bioscience 7195/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7195/50

catalog :

7195/50

quantity :

50 mg

price :

146 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Dentoni G, Naia L, Ankarcrona M. Mitochondria-Endoplasmic Reticulum Interplay Regulates Exo-Cytosis in Human Neuroblastoma Cells. Cells. 2022;11: pubmed publisher

image

image 1 :

Cat.No. 7195 - MCU i4 C23H27N3O2 CAS No. 371924-24-2

product information

master code :

7195

SKU :

7195/50

product name :

MCU i4

unit size :

50 mg

description :

Negative modulator of mitochondrial Ca2+ uniporter (MCU)

target :

Mitochondrial Calcium Uniporter Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

377.49

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MCU i4 is a negative modulator of mitochondrial calcium (Ca2+) uniporter (MCU) complex, which binds to MICU1, a regulatory protein within MCU complex. MCU i4 reduces mitochondrial Ca2+ uptake in multiple cell lines including MEFs, MDA-MB,231 and HEK293T cells, and demonstrates a negative effect on mitochondrial membrane potential. In ex vivo muscle fibres, MCU i4 reduces mitochondrial Ca2+ uptake and impairs muscle cell growth.

top caption :

Negative modulator of mitochondrial Ca2+ uniporter (MCU)

extended description :

Negative modulator of mitochondrial Ca2+ uniporter (MCU)

chemical name text :

4-[[4-(Diethylamino)phenyl]amino]-6-methyl-3-quinolinecarboxylic acid ethyl ester

formula :

C23H27N3O2

formula text :

C23H27N3O2

cas num :

371924-24-2

USD :

146 USD

product details :

Negative modulator of mitochondrial Ca2+ uniporter (MCU)

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage