7191/10 | Tocris Bioscience 7191/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7191/10

catalog :

7191/10

quantity :

10 mg (also 50 mg)

price :

87 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Calabrese B, Jones S, Shiraishi Yamaguchi Y, Lingelbach M, Manor U, Svitkina T, et al. INF2-mediated actin filament reorganization confers intrinsic resilience to neuronal ischemic injury. Nat Commun. 2022;13:6037 pubmed publisher

image

image 1 :

Cat.No. 7191 - Santacruzamate A C15H22N2O3 CAS No. 1477949-42-0

product information

master code :

7191

SKU :

7191/10

product name :

Santacruzamate A

unit size :

10 mg (also 50 mg)

description :

Highly potent and selective HDAC2 inhibitor

target :

Class II Histone Deacetylases Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

278.35

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Santacruzamate A is a highly potent and selective histone deactylase 2 (HDAC2) inhibitor (IC50 = 112 - 119 pM). Also inhibits HDAC6 in nanomolar range (IC50 = 433 nM). Displays 3500 fold selectivity for HDAC2 over HDAC6, and 8500-fold selectivity over HDAC4 (IC50 1 M for HDAC4). Inhibits growth of HuT-78 cutaneous T-cell lymphoma cell line. Identified as targeting human host proteins that interact with SARS-CoV-2.

top caption :

Highly potent and selective HDAC2 inhibitor

extended description :

Highly potent and selective HDAC2 inhibitor

chemical name text :

Ethyl N-[4-oxo-4-[(2-phenylethyl)amino]butyl]carbamate

formula :

C15H22N2O3

formula text :

C15H22N2O3

cas num :

1477949-42-0

USD :

87 USD

product details :

Highly potent and selective HDAC2 inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage