Chroman 1 | Tocris Bioscience 7163 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Chroman 1

catalog :

7163

quantity :

10 mg (also 50 mg)

price :

316 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7163 - Chroman 1 C24H28N4O4.2HCl

product information

brand :

Tocris

master code :

7163

SKU :

7163/10

product name :

Chroman 1

description :

Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogeneisis

target :

Rho-kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

509.43

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Highly potent and selective ROCK2 inhibitor (IC50 values are 1 and 52 pM at ROCK2 and ROCK1, respectively). Exhibits selectivity over a range of related kinases including PKA, AKT1 and MRCK (IC50 values are 20000, 20000 and 150 nM respectively). Improves cell survival after cryogenesis. Also promotes survival of stem cells in culture.

catalog number base :

7163

product keywords :

Selective p160 ROCK inhibitors inhibits Rho-Kinase Rho-Associated Coiled-Coil Kinases ROK stem cells organoids induced pluripotent ROCKI ROCK1 ROCKII ROCK2 reprogramming cryopreservation differentiation cell freezing media cryogenesis self renewed Rho-kinases Stem Cell Proliferation Stem Cell Reprogramming Organoids Neural Stem Cells 7163,

extended description :

Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogeneisis

chemical name text :

(3S)-N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-3,4-dihydro-6-methoxy-2H-1-benzopyran-3-carboxamide dihydrochloride

formula :

C 24 H 28 N 4 O 4 .2HCl

formula text :

C24H28N4O4.2HCl

2020 USD :

309

2021 USD :

316 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage