7157/5 | Tocris Bioscience 7157/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7157/5

catalog :

7157/5

quantity :

5 mg

price :

319 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7157 - YKL 5-124 C28H33N7O3 CAS No. 1957203-01-8

product information

master code :

7157

SKU :

7157/5

product name :

YKL 5-124

unit size :

5 mg

description :

Potent and selective CDK7 inhibitor; induces cell cycle arrest

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

purity :

95%

observed molecular weight :

515.62

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

YKL-5-124 is a potent and selective CDK7/Mat1/CycH and cyclin dependent kinase (CDK7) inhibitor (IC50 values = 9.7 nM and 53.5 nM, respectively). YKL-5-124 shows 100-fold selectivity over CDK9 and CDK2. YKL-5-124 induces cell cycle arrest at the G1/S transition, inhibits E2F-driven gene expression and inhibits CDK1 and CDK3 T-loop phosphorylation.

top caption :

Potent and selective CDK7 inhibitor; induces cell cycle arrest

extended description :

Potent and selective CDK7 inhibitor; induces cell cycle arrest

chemical name text :

N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[[4-[(1-oxo-2-propen-1-yl)amino]benzoyl]amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide

formula :

C28H33N7O3

formula text :

C28H33N7O3

cas num :

1957203-01-8

USD :

319 USD

product details :

Potent and selective CDK7 inhibitor; induces cell cycle arrest

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage