7153/2 | Tocris Bioscience 7153/2 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7153/2

catalog :

7153/2

quantity :

2 mg (also 10 mg)

price :

186 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7153 - BRD 0539 C25H25FN2O3S CAS No. 1403838-79-8

product information

master code :

7153

SKU :

7153/2

product name :

BRD 0539

unit size :

2 mg (also 10 mg)

description :

Cell permeable and reversible Cas9 inhibitor

target :

CRISPR Reagents

category :

Small Molecules

purity :

98%

observed molecular weight :

452.54

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BRD 0539 is a cell-permeable and reversible SpCas9 ( Streptococcus pyogenes Cas9) inhibitor. BRD 0539 shows dose-dependent SpCas9 inhibition in an in vitro DNA cleavage assay (apparent IC50 = 22 M) and in an eGFP disruption assay (apparent EC50 = 11 M). Allows dose and temporal control of SpCas9-based systems.

top caption :

Cell permeable and reversible Cas9 inhibitor

extended description :

Cell permeable and reversible Cas9 inhibitor

chemical name text :

(3aR,4R,9bR)-8-(2-Fluorophenyl)-2,3,3a,4,5,9b-hexahydro-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[3,2-c]quinoline-4-methanol

formula :

C25H25FN2O3S

formula text :

C25H25FN2O3S

cas num :

1403838-79-8

USD :

186 USD

product details :

Cell permeable and reversible Cas9 inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage