7143/10 | Tocris Bioscience 7143/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7143/10

catalog :

7143/10

quantity :

10 mg (also 50 mg)

price :

113 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7143 - VX 765 C24H33ClN4O6 CAS No. 273404-37-8

product information

master code :

7143

SKU :

7143/10

product name :

VX 765

unit size :

10 mg (also 50 mg)

description :

High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable

target :

Caspase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

509

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

VX 765 is a high affinity and selective caspase-4 and caspase 1/ICE inhibitor (Ki of 0.6 and 0.8 nM, respectively). Prodrug of VRT-043198. Inhibits LPS-induced IL-1 production ~ 60% in collagen-induced arthritis mouse model. Exhibits anticonvulsant effects in mouse model of acute seizures. Anti-inflammatory. Orally bioavailable.

top caption :

High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable

extended description :

High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable

chemical name text :

N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide

formula :

C24H33ClN4O6

formula text :

C24H33ClN4O6

cas num :

273404-37-8

USD :

113 USD

product details :

High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable

alt names :

Belnacasan

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage