7131/5 | Tocris Bioscience 7131/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7131/5

catalog :

7131/5

quantity :

5 mg

price :

234 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7131 - TM 38837 C30H25Cl2F3N4OS CAS No. 1253641-65-4

product information

master code :

7131

SKU :

7131/5

product name :

TM 38837

unit size :

5 mg

description :

Highly potent CB1 inverse agonist; peripherally restricted

target :

Cannabinoid R1 / CB1 Inverse Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

617.51

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TM 38837 is a highly potent cannabinoid 1 receptor (CB1) inverse agonist (IC50 values are 8.5 nM and 605 nM for inhibition of [3H]-CP 55940 binding at CB1 and CB2 receptors, respectively). Displays 71-fold selectivity for CB1 receptors over CB2 receptors. Inhibits GTP binding to CB1-overexpressing cell membranes in vitro (EC50 = 18.5 nM). Peripherally restricted. Promotes fear behaviors when given by intracerebrovascular (icv) injection in mice.

top caption :

Highly potent CB1 inverse agonist; peripherally restricted

extended description :

Highly potent CB1 inverse agonist; peripherally restricted

chemical name text :

1-(2,4-Dichlorophenyl)-4-ethyl-N-1-piperidinyl-5-[5-[2-[4-(trifluoromethyl)phenyl]ethynyl]-2-thienyl]-1H-pyrazole-3-carboxamide

formula :

C30H25Cl2F3N4OS

formula text :

C30H25Cl2F3N4OS

cas num :

1253641-65-4

USD :

234 USD

product details :

Highly potent CB1 inverse agonist; peripherally restricted

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage