7130/1 | Tocris Bioscience 7130/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7130/1

catalog :

7130/1

quantity :

1 mg

price :

200 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

AZD 5248 CAS No. 1254318-44-9 Potent cathepsin C inhibitor

product information

master code :

7130

SKU :

7130/1

product name :

AZD 5248

unit size :

1 mg

description :

Potent cathepsin C inhibitor

target :

Synthetic Cathepsin Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

374.44

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AZD 5248 is a potent cathepsin C (also known as dipeptidyl peptidase 1, or DPP1) inhibitor (IC50 values are 44 and 67 nM for human and rat, respectively). In vivo , AZD 5248 inhibition of cathepsin C correlates to the reduction of NSP (neutrophil serine protease) activity measured in rat bone marrow and blood. In rats, quantitative whole-body autoradiography studies demonstrate aortic binding of AZ 5248. This compound is orally bioavailable.

top caption :

Potent cathepsin C inhibitor

extended description :

Potent cathepsin C inhibitor

chemical name text :

4-Amino-N-[(1S)-1-cyano-2-(4 -cyano[1,1 -biphenyl]-4-yl)ethyl]tetrahydro-2H-pyran-4-carboxamide

formula :

C22H22N4O2

formula text :

C22H22N4O2

cas num :

1254318-44-9

USD :

200 USD

product details :

Potent cathepsin C inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage