product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
7122/10
catalog :
7122/10
quantity :
10 mg
price :
61 USD
more info or order :
image
image 1 :
Tocris Bioscience 7122/10 image 1
Fluorescent amyloid stain, binds to the stacked sheets of amyloid fibrils
product information
master code :
7122
SKU :
7122/10
product name :
Thioflavin T
unit size :
10 mg
description :
Cell-permeable fluorescent amyloid stain. Used for: in vitro A staining in brain tissues.
target :
Fluorescent Amyloid B Probes
category :
Small Molecules
purity :
95%
observed molecular weight :
318.86
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Key information : Thioflavin T is a cell-permeable fluorescent amyloid stain. . Used for : staining of insoluble senile plaques of A in brain tissues, monitoring the kinetics of in vitro polyglutamine amyloid formation of tNhtt-42Q aggregates in a Huntington's disease cell model. Thioflavin T is used to confirm formation of sheet structure from mutant huntingtin exon-1 aggregates (Ex1Q48) in vitro . Application : fluorescence microscopy. . Properties and Photophysical Data : Thioflavin T is a cationic benzothiazole. It increases in fluorescence upon strong binding (Ki = 580 nM) to the stacked sheets of amyloid fibrils. Excitation and emission maxima ( ) are 440 nm and 485 nm, respectively; quantum yield = 0.43; extinction coefficient = 31600 M-1cm-1. . This product is supplied with a high degree of hydration and some residual inorganic salts, the amount of which are batch dependent. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.
top caption :
Fluorescent amyloid stain, binds to the stacked sheets of amyloid fibrils
extended description :
Cell-permeable fluorescent amyloid stain. Used for: in vitro A staining in brain tissues.
chemical name text :
2-[4-(Dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chloride
formula :
C17H19ClN2S
formula text :
C17H19ClN2S
cas num :
2390-54-7
USD :
61 USD
product details :
Cell-permeable fluorescent amyloid stain. Used for: in vitro A staining in brain tissues.
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK