AGI 5198 | Tocris Bioscience 7087 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AGI 5198

catalog :

7087

quantity :

25 mg

price :

419 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7087 - AGI 5198 C27H31FN4O2 CAS No. 1355326-35-0

product information

brand :

Tocris

master code :

7087

SKU :

7087/25

product name :

AGI 5198

description :

Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1)

target :

Dehydrogenase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

462.56

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1; IC50 = 70 nM). Selective for mIDH1 over wild-type IDH1 and IDH2. Inhibits production of oncometabolite D-2 hydroxyglutarate. Attenuates growth of glioma cells containing mIDH1, but not wild-type IDH1, in vitro and in vivo . Also inhibits growth of fibrosarcoma and chondrosarcoma cells bearing mIDH1.

catalog number base :

7087

product keywords :

AGI5198 potent selective inhibitor inhibits mutant isocitrate dehydrogenase 1 mIDH1 oncometabolites D-2 hydroxyglutarate D-2HG Isocitrate dehydrogenase 1 (IDH1) 7087,

extended description :

Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1)

chemical name text :

N-[2-(Cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-2-methyl-1H-Imidazole-1-acetamide

formula :

C 27 H 31 FN 4 O 2

formula text :

C27H31FN4O2

cas num :

1355326-35-0

2020 USD :

419

2021 USD :

419 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage