DL 175 | Tocris Bioscience 7082 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

DL 175

catalog :

7082

quantity :

10 mg (also 50 mg)

price :

109 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7082 - DL 175 C17H14ClNO2

product information

brand :

Tocris

master code :

7082

SKU :

7082/10

product name :

DL 175

description :

Potent and selective GPR84 agonist

target :

Free Fatty Acid Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

299.75

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective GPR84 biased agonist (EC50 = 33 nM). Exhibits no significant activity in a panel of 168 other GPCRs. Exhibits bias for G protein signaling pathways. Induces morphological changes in primary murine bone marrow-derived macrophages (BMDMs) in a cellular impedance assay, and promotes phagocytosis by M1 polarized U937 cells. Induces migration of primary human monocytes, but has no effect on macrophage chemotaxis.

catalog number base :

7082

product keywords :

DL175 GPR84 potent selective agonists agonism macrophages monocytes chemotaxis phagocytosis Free Fatty Acid Receptors 7082,

extended description :

Potent and selective GPR84 agonist

chemical name text :

3-(2-((4-Chloronaphthalen-1-yl)oxy)ethyl)pyridine 1-oxide

formula :

C 17 H 14 ClNO 2

formula text :

C17H14ClNO2

2020 USD :

109

2021 USD :

109 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage