product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
7065/1
catalog :
7065/1
quantity :
1 mg (also 10 mg, 50 mg)
price :
103 USD
more info or order :
image
image 1 :
Tocris Bioscience 7065/1 image 1
Kainate agonist; excitant and neurotoxin
product information
master code :
7065
SKU :
7065/1
product name :
Kainic acid (synthetic)
unit size :
1 mg (also 10 mg, 50 mg)
description :
Kainate agonist; excitant and neurotoxin
target :
Kainate Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
213.23
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Kainic acid, also known as kainate, is a selective agonist of kainate ionotropic glutamate receptors (EC50 = 0.6 M - 7.4 M) and a partial agonist at AMPA receptors (EC50 = 31 M - 170 M). Kainic acid is used to model epilepsy in vivo and to study the mechanisms of neurodegeneration and neurocytosis induced by excess stimulation by kainic acid. Kainate is shown to be involved in amyloidogenic processing of amyloid precursor protein and A peptides in Alzheimer s. Synthetic version of Kainic acid (Cat. No. 0222) . Related compounds include the kainate receptor agonist Domoic acid (Cat. No. 0269) and the antagonist NBQX (Cat. No. 0373).
top caption :
Kainate agonist; excitant and neurotoxin
extended description :
Kainate agonist; excitant and neurotoxin
chemical name text :
(2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid
formula :
C10H15NO4
formula text :
C10H15NO4
cas num :
487-79-6
USD :
103 USD
product details :
Kainate agonist; excitant and neurotoxin
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK