7055/10 | Tocris Bioscience 7055/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7055/10

catalog :

7055/10

quantity :

10 mg (also 50 mg)

price :

189 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7055 - WS 383 C18H20ClN9S2.HCl CAS No. 2247544-02-9

product information

master code :

7055

SKU :

7055/10

product name :

WS 383

unit size :

10 mg (also 50 mg)

description :

Potent, selective and reversible DCN1-UBC12 interaction inhibitor

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

498.45

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

WS 383 is a potent and reversible DCN1-UBC12 interaction inhibitor (IC50 = 11 nM). The compound displays selectivity for DCN1-UBC12 over inhibition of a panel of kinases. including Bruton s tyrosine kinase (BTK), cyclin-dependent kinases (CDKs) and epidermal growth factor receptor (EGFR). In vitro , WS 383 selectively inhibits cullin-3 neddylation over other cullins, and induces accumulation of p21, p27 and NRF2.

top caption :

Potent, selective and reversible DCN1-UBC12 interaction inhibitor

extended description :

Potent, selective and reversible DCN1-UBC12 interaction inhibitor

chemical name text :

5-[[2-[[(4-Chlorophenyl)methyl]thio]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]thio]-N,N-dimethyl-1H-tetrazole-1-ethanamine hydrochloride

formula :

C18H20ClN9S2.HCl

formula text :

C18H20ClN9S2.HCl

cas num :

2247544-02-9

USD :

189 USD

product details :

Potent, selective and reversible DCN1-UBC12 interaction inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage