7054/10 | Tocris Bioscience 7054/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7054/10

catalog :

7054/10

quantity :

10 mg (also 50 mg)

price :

112 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7054 - T4 C22H23N3O3 CAS No. 785708-33-0

product information

master code :

7054

SKU :

7054/10

product name :

unit size :

10 mg (also 50 mg)

description :

Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3

target :

DNA, RNA and Protein Synthesis Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

377.44

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

T4 is a modulator of alternative polyadenylation (APA) (IC50 values are 2.1 M and 8.5 M in U2OS and 293T cells, respectively). T4 promotes distal-to-proximal APA usage in multiple transcripts, using distinctive A-rich motifs through autoregulated PABPN1 signaling. T4 exhibits no inhibitory activity against a panel of 414 kinases. T4 prevents retinal degeneration in the RhoP23H mouse model of retinitis pigmentosa. T4 inhibits rod photoreceptor gene expression via Nr2e3 in a luciferase-based assay (IC50 = 0.07 M).

top caption :

Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3

extended description :

Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3

chemical name text :

6,7-Dimethoxy-2-[((4-phenyl-3,6-dihydropyridin-1(2H)-yl)methyl)]quinazolin-4(3H)-one

formula :

C22H23N3O3

formula text :

C22H23N3O3

cas num :

785708-33-0

USD :

112 USD

product details :

Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage