(+/-)-a-Lipoamide | Tocris Bioscience 7045 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

(+/-)-a-Lipoamide

catalog :

7045

quantity :

100 mg

price :

89 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7045 - (?)-a-Lipoamide C8H15NOS2 CAS No. 940-69-2

product information

brand :

Tocris

master code :

7045

SKU :

7045/100

product name :

(+/-)-a-Lipoamide

description :

Phase-separated condensate modifier; orally bioavailable

target :

Buffers, Chelators and Reagents

category :

Small Molecules

unit size :

100 mg

purity :

98%

observed molecular weight :

205.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Phase-separated condensate modifier. Reduces propensity of stress granule proteins to aggregate (EC50 = 20 M in HeLa and iPSCs), and causes FUS stress granule proteins to return to the nucleus in vitro . Stimulates mitochondrial biogenesis in 3T3-L1 adipocytes. Prevents dieback of ALS patient-derived (FUS mutant) motor neuron axons in culture, and recovers motor defects in D. melanogaster expressing FUS mutants. Suppresses the effects of ALS-associated FUS mutations in vivo in different systems. Orally bioavailable.

catalog number base :

7045

product keywords :

Phase-separated condensate modifier liquid-liquid phase separation LLPS liquid-like solid-like assemblies probe membrane-less compartments disrupts dissolves Biochemicals and Molecular Biology 7045,

extended description :

Phase-separated condensate modifier; orally bioavailable

chemical name text :

1,2-Dithiolane-3-pentanamide

formula :

C 8 H 15 NOS 2

formula text :

C8H15NOS2

cas num :

940-69-2

2020 USD :

2021 USD :

89 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage