7040/10 | Tocris Bioscience 7040/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7040/10

catalog :

7040/10

quantity :

10 mg (also 50 mg)

price :

78 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Shamseddine A, Patel S, Chávez V, Moore Z, Adnan M, Di Bona M, et al. Innate immune signaling drives late cardiac toxicity following DNA-damaging cancer therapies. J Exp Med. 2023;220: pubmed publisher

image

image 1 :

Cat.No. 7040 - C 176 C11H7IN2O4 CAS No. 314054-00-7

product information

master code :

7040

SKU :

7040/10

product name :

C 176

unit size :

10 mg (also 50 mg)

description :

mSTING antagonist

target :

STING Antagonists

category :

Small Molecules

purity :

97%

observed molecular weight :

358.09

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

C 176 is a mSTING antagonist. Covalently binds Cys91 of mouse but not human STING. Blocks activation-induced palmitoylation of STING and formation of STING clusters. Reduces CMA (Cat. No. 6677) -induced increase in serum IFNs in vivo and suppresses systemic inflammation in a mouse inflammatory disease model.

top caption :

mSTING antagonist

extended description :

mSTING antagonist

formula :

C11H7IN2O4

formula text :

C11H7IN2O4

cas num :

314054-00-7

USD :

78 USD

product details :

mSTING antagonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage