Palonosetron hydrochloride | Tocris Bioscience 7038 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Palonosetron hydrochloride

catalog :

7038

quantity :

10 mg (also 50 mg)

price :

65 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7038 - Palonosetron hydrochloride C19H24N2O.HCl CAS No. 135729-62-3

product information

brand :

Tocris

master code :

7038

SKU :

7038/10

product name :

Palonosetron hydrochloride

description :

Highly potent and high affinity 5-HT3 antagonist

target :

5-HT3 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

332.87

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Highly potent and high affinity 5-HT3 antagonist (IC50 = 0.24 nM for 5-HT3A; pKi = 10.4). Displays a slow dissociation rate. Inhibits 5-HT-induced enhancement of cellular response to substance P (Cat. No. 1156) in vitro . Inhibits cisplatin (Cat. No. 2251)-induced enhancement of substance P response in vivo .

catalog number base :

7038

product keywords :

serotonin 5-HT3 receptor antagonist antagonism highly potent high potency affinity antiemtic chemotherapy induced vomiting nausea 5-HT3 Receptors 7038,

extended description :

Highly potent and high affinity 5-HT3 antagonist

chemical name text :

(3aS)-2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one hydrochloride

formula :

C 19 H 24 N 2 O.HCl

formula text :

C19H24N2O.HCl

cas num :

135729-62-3

2020 USD :

2021 USD :

65 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage