GX 201 | Tocris Bioscience 7029 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GX 201

catalog :

7029

quantity :

10 mg

price :

265 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7029 - GX 201 C25H27ClF4N2O4S CAS No. 1788071-27-1

product information

brand :

Tocris

master code :

7029

SKU :

7029/10

product name :

GX 201

description :

Potent and selective Nav1.7 blocker; analgesic

target :

Voltage-gated Sodium Channel Blockers

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

563

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective Nav1.7 blocker (IC50 = 3.2 nM). Exhibits 10x selectivity for Nav1.7 over Nav1.1, Nav1.2, and Nav1.6 channels. Displays prolonged residency time on the Nav1.7 channel. Chronic dosing increases compound potency ~10-fold and provides efficacy that persists after the compound has cleared from plasma. Suppresses neuropathic pain in a mouse diabetic neuropathy model. Analgesic.

catalog number base :

7029

product keywords :

GX201 Potent selective Nav1.7 voltage-gated Sodium NaV Channels blockers blocks inhibitors inhibits blockers neuropathic pain slow dissociation Voltage-gated Sodium Channels 7029,

extended description :

Potent and selective Nav1.7 blocker; analgesic

chemical name text :

4-[[1-[[2-Chloro-5-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methoxy]-5-cyclopropyl-2-fluoro-N-(methylsulfonyl)benzamide

formula :

C 25 H 27 ClF 4 N 2 O 4 S

formula text :

C25H27ClF4N2O4S

cas num :

1788071-27-1

2020 USD :

265

2021 USD :

265 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage