7010/10 | Tocris Bioscience 7010/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7010/10

catalog :

7010/10

quantity :

10 mg

price :

296 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7010 - EM 163 C44H60IN5O4 CAS No. 1206480-93-4

product information

master code :

7010

SKU :

7010/10

product name :

EM 163

unit size :

10 mg

description :

TIR-TIR interaction inhibitor

target :

Cytokine Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

849.9

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

EM 163 is a TIR-TIR interaction inhibitor, that is a TIR (Toll/ interleukin-1 receptor) domain peptidomimetic of MyD88 protein. EM 163 targets TIR domains in IL-1 receptors blocking the interaction with MyD88. EM 163 inhibits staphylococcal enterotoxin B (SEB)-induced inflammatory cytokine production in vivo . EM 163 protects mice from SEB shock-induced death. In rat hippocampal neurons in vitro , EM 163 blocks the activation of p38 and the inhibitory effects of IL-1 on protein synthesis triggered by chemically-induced long-term potentiation (LTP).

top caption :

TIR-TIR interaction inhibitor

extended description :

TIR-TIR interaction inhibitor

chemical name text :

1-Methyl-2,5-bis[[[(1S)-2-methyl-1-(1-pyrrolidinylcarbonyl)propyl](3-phenylpropyl)amino]carbonyl]pyridinium iodide

formula :

C44H60IN5O4

formula text :

C44H60IN5O4

cas num :

1206480-93-4

USD :

296 USD

product details :

TIR-TIR interaction inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage