KYA 1797K | Tocris Bioscience 7002 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

KYA 1797K

catalog :

7002

quantity :

25 mg

price :

295 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7002 - KYA 1797K C17H11KN2O6S2 CAS No. 1956356-56-1

product information

brand :

Tocris

master code :

7002

SKU :

7002/25

product name :

KYA 1797K

description :

Wnt/ -catenin signaling inhibitor

target :

beta-Catenin Compounds

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

442.5

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Wnt/ -catenin signaling inhibitor (IC50 = 0.75 M). Increases binding affinity of -catenin for axin, GSK-3 and -TrCP. Promotes formation of the destruction complex, activation of GSK-3 and phosphorylation of -catenin and K-Ras, leading to their degradation via the ubiquitin/proteasome system. Reduces levels of -catenin and K-Ras and inhibits growth of colorectal cancer (CRC) cells in vitro and in mouse xenograft models.

catalog number base :

7002

product keywords :

KYA1797K wnt beta catenin signaling pathway inhibitors inhibits K-Ras destruction complex promotes Beta-catenin 7002,

extended description :

Wnt/ -catenin signaling inhibitor

chemical name text :

(5Z)-5-[[5-(4-Nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid potassium salt

formula :

C 17 H 11 KN 2 O 6 S 2

formula text :

C17H11KN2O6S2

cas num :

1956356-56-1

2020 USD :

295

2021 USD :

295 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage