AT 7867 | Tocris Bioscience 7001 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AT 7867

catalog :

7001

quantity :

10 mg (also 50 mg)

price :

149 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7001 - AT 7867 C20H20ClN3.HCl

product information

brand :

Tocris

master code :

7001

SKU :

7001/10

product name :

AT 7867

description :

Potent pan-Akt and PKA inhibitor

target :

Akt (Protein Kinase B) Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

374.31

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent pan-Akt (protein kinase B) and protein kinase A (PKA) inhibitor (IC50 values are 32, 17, 47 and 20 nM for Akt1, Akt2, Akt3 and PKA, respectively). Also inhibits p70-S6 kinase (p70S6K, IC50 = 85 nM). Inhibits Akt signaling and proliferation of multiple human cancer cell lines, including breast, prostate and colon. Promotes proliferation of iPSC-derived PDX1+ pancreatic progenitor cells (PPCs).

catalog number base :

7001

product keywords :

AT7867 857531-00-1 Akt inhibitor XVi inhibits Akt1 Akt2 Akt3 PKA protein kinase B A p70S6K pancreatic progenitor cells poliferation stem cells Akt (Protein Kinase B) Protein Kinase A Other Kinases Stem Cell Proliferation 7001,

extended description :

Potent pan-Akt and PKA inhibitor

chemical name text :

4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine hydrochloride

formula :

C 20 H 20 ClN 3 .HCl

formula text :

C20H20ClN3.HCl

2020 USD :

149

2021 USD :

149 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage