6998/5 | Tocris Bioscience 6998/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6998/5

catalog :

6998/5

quantity :

5 mg

price :

393 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zhang Y, Guo R, Kim S, Shah H, Zhang S, Liang J, et al. SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication. Nat Commun. 2021;12:1676 pubmed publisher

image

image 1 :

Cat.No. 6998 - SHIN 1 C24H24N4O2 CAS No. 2146095-85-2

product information

master code :

6998

SKU :

6998/5

product name :

SHIN 1

unit size :

5 mg

description :

Potent SHMT inhibitor

target :

Other Transferase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

400.48

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SHIN 1 is a potent serine hydroxymethyltransferase (SHMT) inhibitor (IC50 values are 5 and 13 nM at SHMT1 and SHMT2, respectively). Inhibits growth of HCT-116 cells in vitro (IC50 = 870 nM). Unstable in liver microsome assays.

top caption :

Potent SHMT inhibitor

extended description :

Potent SHMT inhibitor

chemical name text :

6-Amino-1,4-dihydro-4-[5-(hydroxymethyl)[1,1 -biphenyl]-3-yl]-3-methyl-4-(1-methylethyl)pyrano[2,3-c]pyrazole-5-carbonitrile

formula :

C24H24N4O2

formula text :

C24H24N4O2

cas num :

2146095-85-2

USD :

393 USD

product details :

Potent SHMT inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage