TL 0259 | Tocris Bioscience 6981/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TL 0259

catalog :

6981/10

quantity :

10 mg (also 50 mg)

price :

322 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6981 - TL 0259 C32H34F3N5O4.2HCl

product information

brand :

Tocris

master code :

6981

SKU :

6981/10

product name :

TL 0259

unit size :

10 mg (also 50 mg)

seo description :

Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable

target :

Src Family Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

682.56

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TL 0259 is a selective and highly potent Fgr and Lyn inhibitor (IC50 values are 0.03 and 0.1 nM, respectively). Exhibits selectivity for Fgr and Lyn over other Src family kinases and other nonreceptor and receptor tyrosine kinases. Suppresses proliferation of acute myelogenous leukemia (AML) cell lines in vitro . Eliminates leukemic cells from spleen and bone of mice bearing AML xenografts. Orally bioavailable.

top caption :

Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable

extended description :

Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable

chemical name text :

3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide dihydrochloride

formula :

C32H34F3N5O4.2HCl

formula text :

C32H34F3N5O4.2HCl

cas num :

2415263-06-6

USD :

322 USD

product details :

Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage