AZD 5363 | Tocris Bioscience 6978/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZD 5363

catalog :

6978/5

quantity :

5 mg (also 25 mg)

price :

172 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6978 - AZD 5363 C21H25ClN6O2 CAS No. 1143532-39-1

product information

brand :

Tocris

master code :

6978

SKU :

6978/5

product name :

AZD 5363

unit size :

5 mg (also 25 mg)

seo description :

Potent pan-AKT inhibitor

target :

Akt (Protein Kinase B) Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

428.92

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AZD 5363 is a potent pan-AKT inhibitor (IC50 values are 3, 7 and 7 nM for AKt 1, 2 and 3, respectively). Also inhibits P70S6K, PKA, ROCK2 and ROCK1 (IC50 values are 6, 7, 60 and 470 nM, respectively). Inhibits growth of tumor cell lines in vitro , particularly breast, endometrial, gastric, hematologic and prostate cancers. Inhibits growth of human tumor xenografts in mice. Enhances in vivo antitumor effects of Docetaxel (Cat. No. 4056) and Lapatinib (Cat. No. 6811). Orally bioavailable.

top caption :

Potent pan-AKT inhibitor

extended description :

Potent pan-AKT inhibitor

chemical name text :

4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinecarboxamide

formula :

C21H25ClN6O2

formula text :

C21H25ClN6O2

cas num :

1143532-39-1

USD :

172 USD

product details :

Potent pan-AKT inhibitor

alt names :

Capivasertib

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage