JNJ 10198409 | Tocris Bioscience 6976 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JNJ 10198409

catalog :

6976

quantity :

10 mg (also 50 mg)

price :

225 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6976 - JNJ 10198409 C18H16FN3O2 CAS No. 627518-40-5

product information

brand :

Tocris

master code :

6976

SKU :

6976/10

product name :

JNJ 10198409

description :

Potent PDGFR and PDGFR inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases

target :

PDGF Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

325.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent platelet-derived growth factor receptor (PDGFR) inhibitor (IC50 values are 4.2 and 45 nM for PDGFR and PDGFR , respectively). Also inhibits c-Abl, Lck, c-Src and Fyn kinases (IC50 values are 22, 100, 185 and 378 nM respectively). Displays antiproliferative activity in multiple tumor cell lines. Accelerates down regulation of fibroblast genes in reprogramming of human fibroblasts into functional cardiomyocytes, within 9C cocktail.

catalog number base :

6976

product keywords :

JNJ10198409 stem cell reprogramming 9C cocktail cardiomyocytes myocytes platelet-derived growth factor receptor alpha beta inhibitors inhibits PDGFR PDGFRb PDGFRa PDGFR Src Kinases Other Kinases Stem Cell Reprogramming 6976,

extended description :

Potent PDGFR and PDGFR inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases

chemical name text :

N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine

formula :

C 18 H 16 FN 3 O 2

formula text :

C18H16FN3O2

cas num :

627518-40-5

2020 USD :

225

2021 USD :

225 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage