NS 3728 | Tocris Bioscience 6973/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NS 3728

catalog :

6973/10

quantity :

10 mg (also 50 mg)

price :

178 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6973 - NS 3728 C16H9BrF6N6O CAS No. 265646-85-3

product information

brand :

Tocris

master code :

6973

SKU :

6973/10

product name :

NS 3728

unit size :

10 mg (also 50 mg)

seo description :

VRAC blocker

target :

Other Chloride Channel Blockers

category :

Small Molecules

purity :

98%

observed molecular weight :

495.18

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NS 3728 is a volume-regulated anion channel (VRAC) blocker (IC50 = 460 nM). Blocks red blood cell chloride conductance (IC50 = 0.6 M). NS 3728 also inhibits Ca2+-activated Cl- current (CaCC) by anoctamin (ANO) in an apparently voltage-dependent manner (IC50 against ANO1 = 2.1 and 0.7 M at -95 and +50 mV, respectively).

top caption :

VRAC blocker

extended description :

VRAC blocker

chemical name text :

N-[3,5-bis(Trifluoromethyl)phenyl]-N -[4-bromo-2-(2H-tetrazol-5-yl)phenyl]urea

formula :

C16H9BrF6N6O

formula text :

C16H9BrF6N6O

cas num :

265646-85-3

USD :

178 USD

product details :

VRAC blocker

alt names :

Endovion

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage