A 1899 | Tocris Bioscience 6972 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

A 1899

catalog :

6972

quantity :

25 mg

price :

349 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6972

SKU :

6972/25

product name :

A 1899

description :

Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker

target :

Two-P Potassium Channels Blockers

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

500.55

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) channel blocker (IC50 values are 7 nM and 70 nM for human TASK-1 and TASK-3 expressed in CHO cells, respectively). Displays 12.5-fold selectivity for TASK-1 and TASK-3 over other K+ channels (IC50 = 0.9 M for K2P18.1/TRESK and 2 M for all other channels tested). Binds within open channel pore.

catalog number base :

6972

product keywords :

A1899 potassium channel two pore blockers blocks task1 task-1 task3 task-1 potent Two-P Potassium Channels 6972,

extended description :

Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker

chemical name text :

N-[(2,4-Difluorophenyl)methyl]-2 -[[[2-(4-methoxyphenyl)acetyl]amino]methyl][1,1 -biphenyl]-2-carboxamide

formula :

C 30 H 26 F 2 N 2 O 3

formula text :

C30H26F2N2O3

cas num :

498577-46-1

2020 USD :

349

2021 USD :

349 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage