Reparixin L-lysine salt | Tocris Bioscience 6957 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Reparixin L-lysine salt

catalog :

6957

quantity :

10 mg

price :

162 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6957

SKU :

6957/10

product name :

Reparixin L-lysine salt

description :

Potent CXCR1 and CXCR2 allosteric antagonist

target :

Chemokine Receptor Antagonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

429.58

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and noncompetitive CXCR1 and CXCR2 allosteric antagonist (IC50 = 1 nM for inhibition of CXCL8-induced human polymorphonuclear cell migration). Also inhibits migration of rodent neutrophils induced by CXCL1, CXCL2, CXCL8 and CINC-1. Inhibits vascular permeability and neutrophil recruitment in in vivo models of mild and severe ischemia/reperfusion injury. Also selectively depletes cancer stem cells in human breast cancer cell lines and xenograft models.

catalog number base :

6957

product keywords :

repertaxin CXCR1 CXCR2 chemokine receptor antagonists antagonism allosteric noncompetitive IL-8 receptor CXCL8 interleukin 8 Repertaxin L-lysine salt Chemokine CXC Receptors Cancer Stem Cells 6957,

extended description :

Potent CXCR1 and CXCR2 allosteric antagonist

chemical name text :

( R)- -Methyl-4-(2-methylpropyl)-N-(methylsulfonyl)benzeneacetamide L-Lysine salt

formula :

C 14 H 21 NO 3 S.C 6 H 14 N 2 O 2

formula text :

C14H21NO3S.C6H14N2O2

cas num :

266359-93-7

2020 USD :

155

2021 USD :

162 USD

alt names :

Repertaxin L-lysine salt

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage