CRBN-6-5-5-VHL | Tocris Bioscience 6948/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CRBN-6-5-5-VHL

catalog :

6948/5

quantity :

5 mg

price :

442 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6948

SKU :

6948/5

product name :

CRBN-6-5-5-VHL

unit size :

5 mg

seo description :

Potent and selective cereblon Degrader (PROTAC cell-permeable

target :

Active Degraders

category :

Small Molecules

purity :

96%

observed molecular weight :

972.21

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CRBN-6-5-5-VHL is a potent and selective cereblon Degrader (PROTAC ) (DC50 = 1.5 nM). Induces complete degradation of cereblon in MM1S cells. Comprises a cereblon E3 ligase ligand joined by a linker to a ligand for the E3 ligase VHL. Cell-permeable. . CRBN antibody validated for Simple Western (automated Western) instruments and Western Blot also available: Catalog # NBP1-91810 . . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

Application of CRBN-6-5-5-VHL in MM1S cells for CRBN-6-5-5-VHL

extended description :

Potent and selective cereblon Degrader (PROTAC cell-permeable

chemical name text :

(2S,4R)-1-((2S)-2-(5-((5-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)oxy)pentyl)oxy)pentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

formula :

C51H69N7O10S

formula text :

C51H69N7O10S

cas num :

2362575-45-7

USD :

442 USD

product details :

Potent and selective cereblon Degrader (PROTAC cell-permeable

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage