dBRD9-A | Tocris Bioscience 6943/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

dBRD9-A

catalog :

6943/5

quantity :

5 mg

price :

432 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
St Pierre R, Collings C, Sam xe9 Guerra D, Widmer C, Bolonduro O, Mashtalir N, et al. SMARCE1 deficiency generates a targetable mSWI/SNF dependency in clear cell meningioma. Nat Genet. 2022;54:861-873 pubmed publisher

image

image 1 :

Cat.No. 6943 - dBRD9-A C42H49N7O8 CAS No. 2170679-42-0

product information

brand :

Tocris

master code :

6943

SKU :

6943/5

product name :

dBRD9-A

unit size :

5 mg

seo description :

Potent BRD9 Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

779.88

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

dBRD9-A is a potent BRD9 Degrader (PROTAC ). Selectively binds BRD9 and elicits near complete degradation of BRD9 at nanomolar concentrations. Inhibits growth of synovial sarcoma cells in vitro and tumor progression in a synovial sarcoma xenograft mouse model. BRD9 antibody validated for Simple Western (automated Western) instruments and Western Blot also available: Catalog # NBP3-14730 . . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

top caption :

Potent BRD9 Degrader (PROTAC )

extended description :

Potent BRD9 Degrader (PROTAC )

chemical name text :

2-((2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)(methyl)amino)-N-(8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octyl)acetamide

formula :

C42H49N7O8

formula text :

C42H49N7O8

cas num :

2170679-42-0

USD :

432 USD

product details :

Potent BRD9 Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage