Pyr 10 | Tocris Bioscience 6941/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Pyr 10

catalog :

6941/10

quantity :

10 mg (also 50 mg)

price :

163 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6941 - Pyr 10 C18H13F6N3O2S CAS No. 1315323-00-2

product information

brand :

Tocris

master code :

6941

SKU :

6941/10

product name :

Pyr 10

unit size :

10 mg (also 50 mg)

seo description :

Selective TRPC3 inhibitor

target :

TRPC Channel Blockers

category :

Small Molecules

purity :

98%

observed molecular weight :

449.37

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Pyr 10 is a TRPC3 (transient receptor potential canonical 3) channel inhibitor (IC50 = 0.72 M for TRPC3 mediated calcium entry in vitro ), which displays approximately 18-fold selectivity for TRPC3-mediated receptor operated calcium entry (ROCE) over STIM1/Orai1-mediated store operated calcium entry (SOCE). Pyr 10 inhibits NFATc3 activation and inhibits proliferation of rat ventricular cardiac fibroblasts.

top caption :

Selective TRPC3 inhibitor

extended description :

Selective TRPC3 inhibitor

chemical name text :

N-[4-[3,5-bis(Trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide

formula :

C18H13F6N3O2S

formula text :

C18H13F6N3O2S

cas num :

1315323-00-2

USD :

163 USD

product details :

Selective TRPC3 inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage