BSJ-03-204 | Tocris Bioscience 6938/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BSJ-03-204

catalog :

6938/5

quantity :

5 mg

price :

438 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Chernobrovkin A, C xe1 zares K xf6 rner C, Friman T, Caballero I, Amadio D, Martinez Molina D. A Tale of Two Tails: Efficient Profiling of Protein Degraders by Specific Functional and Target Engagement Readouts. SLAS Discov. 2021;26:534-546 pubmed publisher

image

image 1 :

Cat.No. 6938 - BSJ-03-204 C43H48N10O8 CAS No. 2349356-09-6

product information

brand :

Tocris

master code :

6938

SKU :

6938/5

product name :

BSJ-03-204

unit size :

5 mg

seo description :

Selective Cdk4/6 Degrader (PROTAC

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

832.92

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BSJ-03-204 is a selective Cdk4/6 Degrader (PROTAC ). Displays cereblon-dependent degradation with no effect on IKZF1/3 in Molt4 cells. Induces degradation of Cdk4/6 and G1 cell cycle arrest, and inhibits cell proliferation in a mantle cell lymphoma (MCL) cell line. . CDK4 antibodies validated for Simple Western (automated Western) instruments and Western Blot also available: Catalog # AF5254 and NBP1-31308 . . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

Selective Cdk4/6 Degrader (PROTAC )

extended description :

Selective Cdk4/6 Degrader (PROTAC

chemical name text :

N-[4-[4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]butyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide

formula :

C43H48N10O8

formula text :

C43H48N10O8

cas num :

2349356-09-6

USD :

438 USD

product details :

Selective Cdk4/6 Degrader (PROTAC

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage