VU 0467485 | Tocris Bioscience 6932 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0467485

catalog :

6932

quantity :

10 mg (also 50 mg)

price :

199 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6932 - VU 0467485 C17H17FN4O2S CAS No. 1451994-10-7

product information

brand :

Tocris

master code :

6932

SKU :

6932/10

product name :

VU 0467485

description :

Potent and selective positive allosteric modulator of M4 receptors; orally bioavailable and brain penetrant

target :

mAChR M4 Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

360.41

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective positive allosteric modulator of M4 receptor; potentiates activity of ACh at M4 (EC50 values are 26.6 and 78.8 nM at rat and human M4 receptors, respectively). Exhibits selectivity for M4 over human and rat M1-3, 5, and a panel of 200 other pharmacological targets. Displays efficacy in a rat model of antipsychotic activity. Orally bioavailable and brain penetrant.

catalog number base :

6932

product keywords :

VU0467485 positive allosteric modulators selective acetycholine muscarinic receptors M4 antipsychotic orally bioavailable M4 Receptors 6932,

extended description :

Potent and selective positive allosteric modulator of M4 receptors; orally bioavailable and brain penetrant

chemical name text :

5-Amino-N-[(3-fluoro-4-methoxyphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide

formula :

C 17 H 17 FN 4 O 2 S

formula text :

C17H17FN4O2S

cas num :

1451994-10-7

2020 USD :

199

2021 USD :

199 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage