Ceritinib | Tocris Bioscience 6905/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ceritinib

catalog :

6905/10

quantity :

10 mg (also 50 mg)

price :

127 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6905 - Ceritinib C28H36ClN5O3S CAS No. 1032900-25-6

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6905

SKU :

6905/10

product name :

Ceritinib

description :

Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3

target :

ALK Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

558.14

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ceritinib is a highly potent anaplastic lymphoma kinase (ALK) inhibitor (IC50 = 0.2 nM). Also displays potent inhibition of insulin receptor (IR), insulin-like growth factor receptor 1 (IGF1R), serine/threonine-protein kinase STK22D and FLT3 (IC50 values are 7, 8, 23 and 60 nM, respectively). Inhibits tumor growth in Karpas299 and H2228 rat xenograft models.

product keywords :

LDK378 ALK inhibitors inhibits highly potent Anaplastic lymphoma kinase insulin receptor InsR insulin-like growth factor receptor IGF1R FLT3 STK22D LDK378 ALK Insulin and insulin-like Receptors FLT3 6905,

extended description :

Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3

chemical name text :

5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine

formula :

C28H36ClN5O3S

formula text :

C28H36ClN5O3S

cas num :

1032900-25-6

USD :

141

USD 2025 :

127 USD

product details :

Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3

alt names :

LDK378

more info or order :

Tocris Bioscience product webpage