Idasanutlin | Tocris Bioscience 6904/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Idasanutlin

catalog :

6904/10

quantity :

10 mg (also 50 mg)

price :

182 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6904 - Idasanutlin C31H29Cl2F2N3O4 CAS No. 1229705-06-9

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6904

SKU :

6904/10

product name :

Idasanutlin

description :

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction

target :

Ubiquitin Ligase (E3) Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

616.49

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Idasanutlin is a potent MDM2 inhibitor (IC50 = 6 nM in binding assay, and 30 nM in cancer cell proliferation assay). Induces p53 stabilisation, cell cycle arrest and apoptosis in cancer cells expressing wildtype p53. Displays inhibition of tumor growth in the SJSA1 tumor xenograft model. Also inhibits MDR-1 at high concentrations.

product keywords :

RG7388 MDM2 inhibitors inhibitors mdm2 p53 interaction Ubiquitin E3 Ligases p53 6904, E3 Ligase

extended description :

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction

chemical name text :

4-[[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxybenzoic acid

formula :

C31H29Cl2F2N3O4

formula text :

C31H29Cl2F2N3O4

cas num :

1229705-06-9

USD :

180

USD 2025 :

182 USD

product details :

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction

more info or order :

Tocris Bioscience product webpage