Idasanutlin | Tocris Bioscience 6904/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Idasanutlin

catalog :

6904/10

quantity :

10 mg (also 50 mg)

price :

182 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6904 - Idasanutlin C31H29Cl2F2N3O4 CAS No. 1229705-06-9

product information

brand :

Tocris

catalog number base :

6904

SKU :

6904/10

product name :

Idasanutlin

units size :

10 mg (also 50 mg)

description :

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

616.49

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Idasanutlin is a potent MDM2 inhibitor (IC50 = 6 nM in binding assay, and 30 nM in cancer cell proliferation assay). Induces p53 stabilisation, cell cycle arrest and apoptosis in cancer cells expressing wildtype p53. Displays inhibition of tumor growth in the SJSA1 tumor xenograft model. Also inhibits MDR-1 at high concentrations.

top caption :

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction

extended description :

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction

chemical name text :

4-[[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxybenzoic acid

formula :

C31H29Cl2F2N3O4

formula text :

C31H29Cl2F2N3O4

cas num :

1229705-06-9

USD :

182 USD

product details :

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage