Dapansutrile | Tocris Bioscience 6902 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Dapansutrile

catalog :

6902

quantity :

10 mg (also 50 mg)

price :

75 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6902

SKU :

6902/10

product name :

Dapansutrile

description :

NLRP3 inflammasome inhibitor; disrupts inflammasome formation

target :

Inflammasomes Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

133.17

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NLRP3 inflammasome inhibitor that disrupts inflammasome formation. Reduces LPS/ATP-induced IL-1 secretion in human and mouse macrophages in vitro , without affecting TNF levels. Reduces LPS-induced inflammation in vivo . Also reduces joint swelling and markers of inflammation in synovial fluid in a mouse model of acute arthritis. Displays cardioprotective effects in a mouse model of cardiac ischemic reperfusion injury. . OLT1177 is a registered trademark of Olatec Therapeutics LLC in the United States and other countries.

catalog number base :

6902

product keywords :

dapansutrile NLRP3 inflammasome inhibitors inhibits cardioprotective arthritis reperfusion anti inflammatory Inflammasomes 6902,

extended description :

NLRP3 inflammasome inhibitor; disrupts inflammasome formation

chemical name text :

3-(Methylsulfonyl)propanenitrile

formula :

C 4 H 7 NO 2 S

formula text :

C4H7NO2S

cas num :

54863-37-5

2020 USD :

2021 USD :

75 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage