PND 1186 | Tocris Bioscience 6891/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PND 1186

catalog :

6891/10

quantity :

10 mg (also 50 mg)

price :

189 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6891 - PND 1186 C25H26F3N5O3 CAS No. 1061353-68-1

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6891

SKU :

6891/10

product name :

PND 1186

description :

Potent FAK inhibitor; orally bioavailable

target :

Focal Adhesion Kinase Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

501.51

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PND 1186 is a potent FAK inhibitor (IC50 values are 1.5 and 100 nM for recombinant FAK and FAK in breast carcinoma cells, respectively). Promotes caspase activation; triggering apoptosis. Inhibits 4T1 breast carcinoma subcutaneous tumor growth and breast carcinoma cell motility. Decreases spontaneous breast to lung metastasis in pre-clinical models. Orally bioavailable.

product keywords :

PND1186 SR2516 VS4718 SR_2516 VS_4718 potent FAK inhibitors inhibits orally bioavailable caspase activators Focal Adhesion Kinase 6891,

extended description :

Potent FAK inhibitor; orally bioavailable

chemical name text :

2-[[2-[[2-Methoxy-4-(4-morpholinyl)phenyl]amino]-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methylbenzamide

formula :

C25H26F3N5O3

formula text :

C25H26F3N5O3

cas num :

1061353-68-1

USD :

187

USD 2025 :

189 USD

product details :

Potent FAK inhibitor; orally bioavailable

more info or order :

Tocris Bioscience product webpage