ML 335 | Tocris Bioscience 6887/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 335

catalog :

6887/10

quantity :

10 mg (also 50 mg)

price :

147 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Deng S, Liu S, Jin P, Feng S, Tian M, Wei P, et al. Albumin Reduces Oxidative Stress and Neuronal Apoptosis via the ERK/Nrf2/HO-1 Pathway after Intracerebral Hemorrhage in Rats. Oxid Med Cell Longev. 2021;2021:8891373 pubmed publisher
Deng S, Sherchan P, Jin P, Huang L, Travis Z, Zhang J, et al. Recombinant CCL17 Enhances Hematoma Resolution and Activation of CCR4/ERK/Nrf2/CD163 Signaling Pathway After Intracerebral Hemorrhage in Mice. Neurotherapeutics. 2020;17:1940-1953 pubmed publisher

image

image 1 :

Cat.No. 6887 - ML 335 C15H14Cl2N2O3S CAS No. 825658-06-8

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6887

SKU :

6887/10

product name :

ML 335

description :

Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator

target :

Two-P Potassium Channels Activators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

373.25

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML 335 is a selective K2P2.1 (TREK-1; KCNK2) and K2P10.1 (TREK-2; KCNK10) activator (EC50 values of 14.3 M and 5.2 M, respectively); directly stimulates the C-type gate via the K2P modulator pocket. Does not activate K2P4.1 (TRAAK).

product keywords :

ML335 Selective K2P2.1 TREK-1 KCNK2 K2P10.1 TREK-2 KCNK10 activators activates Two-P Potassium Channels 6887,

extended description :

Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator

chemical name text :

N-[(2,4-Dichlorophenyl)methyl]-4-[(methylsulfonyl)amino]benzamide

formula :

C15H14Cl2N2O3S

formula text :

C15H14Cl2N2O3S

cas num :

825658-06-8

USD :

142

USD 2025 :

147 USD

product details :

Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator

more info or order :

Tocris Bioscience product webpage