SB 4 | Tocris Bioscience 6881/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 4

catalog :

6881/50

quantity :

50 mg

price :

99 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Hayaei Tehrani R, Sayahpour F, Esfandiari F. A comparison between BMP4 and SB4 in inducing germ line gene expression pattern during embryonic stem cells differentiation. Differentiation. 2022;123:9-17 pubmed publisher

product information

brand :

Tocris

MasterCode :

6881

SKU :

6881/50

product name :

SB 4

target :

BMP and Other Activin Receptor Activators

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

320.2

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SB 4 is a potent BMP4 agonist (EC50 = 74 nM). Activates canonical BMP signaling and increases SMAD-1/5/9 phosphorylation, with no effect on p-SMAD-2, p-SMAD-3 or p-TAK1. Bypasses noggin-induced inhibition of type I BMP receptors. When used in combination, SB 4 enhances BMP4 signaling and embryonic stem cell differentiation.

extended description :

Potent BMP4 agonist

chemical name text :

2-[[(4-Bromophenyl)methyl]thio]benzoxazole

formula :

C 14 H 10 BrNOS

formula text :

C14H10BrNOS

cas num :

100874-08-6

USD :

99 USD

product details :

Potent BMP4 agonist

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage