VU 0134992 | Tocris Bioscience 6877/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0134992

catalog :

6877/10

quantity :

10 mg (also 50 mg)

price :

225 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Kuroda T, Matsuda N, Ishibashi Y, Suzuki I. Detection of astrocytic slow oscillatory activity and response to seizurogenic compounds using planar microelectrode array. Front Neurosci. 2022;16:1050150 pubmed publisher
Leo M, Schmitt L, Fleischer M, Steffen R, Osswald C, Kleinschnitz C, et al. Induction of Survival of Motor Neuron (SMN) Protein Deficiency in Spinal Astrocytes by Small Interfering RNA as an In Vitro Model of Spinal Muscular Atrophy. Cells. 2022;11: pubmed publisher

image

image 1 :

Cat.No. 6877 - VU 0134992 C20H31BrN2O2 CAS No. 755002-90-5

product information

brand :

Tocris

catalog number base :

6877

SKU :

6877/10

product name :

VU 0134992

units size :

10 mg (also 50 mg)

description :

Kir4.1 blocker

target :

Inward Rectifier Potassium Channel Blockers

category :

Small Molecules

purity :

98%

observed molecular weight :

411.38

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

VU 0134992 is a Kir4.1 potassium channel blocker (IC50 = 0.97 M). Displays 10-fold selectivity for Kir4.1 over Kir4.1/5.1 concatemeric channels and 30-fold selectivity over Kir1.1, 2.1 and 2.2. Increases urine output and urinary Na+ and K+ excretion in volume-loaded rats.

top caption :

Kir4.1 blocker

extended description :

Kir4.1 blocker

chemical name text :

2-(2-Bromo-4-isopropylphenoxy)-N-(2,2,6,6-tetramethylpiperidin-4-yl)acetamide

formula :

C20H31BrN2O2

formula text :

C20H31BrN2O2

cas num :

755002-90-5

USD :

225 USD

product details :

Kir4.1 blocker

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage