DC 271 | Tocris Bioscience 6873/5 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

DC 271

catalog :

6873/5

quantity :

5 mg

price :

234 USD

product information

brand :

Tocris

master code :

6873

SKU :

6873/5

product name :

DC 271

unit size :

5 mg

seo description :

Fluorescent retinoic acid analog; solvochromatic probe

target :

Fluorescent Receptor Probes

category :

Small Molecules

purity :

98%

observed molecular weight :

347.46

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

DC 271 is a fluorescent retinoic acid analog (retinoid all-trans-retinoic acid; ATRA) (Kd = 42 nM at cellular retinoid binding protein II (CRABPII)). Solvochromatic probe: fluorescent ex, em, and quantum yield affected by solvent type. DC 271 can be used in retinoids assays. Activates same genes as endogenous retinoic acid in human keratinocyte cells (HaCaT) when incubated for 72 h at 1 M. Also elicits cellular responses consistent with those of retinoic acid. Excitation = 351, 350, 382 and 378 nm in DMSO, EtOH, DCM and Toluene, respectively; emission = 442, 461, 572 and 447 nm in DMSO, EtOH, DCM and Toluene, respectively. Quantum yield = 19.3, 1.14, 71.45, 80.21 % in DMSO, EtOH, DCM and Toluene, respectively.

top caption :

Fluorescent retinoic acid analog; solvochromatic probe

extended description :

Fluorescent retinoic acid analog; solvochromatic probe

chemical name text :

4-[2-[1,2,3,4-Tetrahydro-4,4-dimethyl-1-(1-methylethyl)-6-quinolinyl]ethynyl]benzoic acid

formula :

C23H25NO2

formula text :

C23H25NO2

cas num :

198696-03-6

USD :

234 USD

product details :

Fluorescent retinoic acid analog; solvochromatic probe

storage :

Store at -20░C