MO-I-500 | Tocris Bioscience 6871/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MO-I-500

catalog :

6871/10

quantity :

10 mg (also 50 mg)

price :

212 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6871 - MO-I-500 C12H12ClNO5S CAS No. 1585219-04-0

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6871

SKU :

6871/10

product name :

MO-I-500

description :

FTO inhibitor; anticonvulsant

target :

Other Oxidase/Oxygenase Compounds

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

317.75

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MO-I-500 is a FTO inhibitor (IC50 = 8.7 M for purified FTO in vitro ), which increases N6-methyladenosine (m6A) levels in total cellular mRNA in HeLa cells. MO-I-500 modulates levels of specific miRNAs. In a triple-negative breast cancer cell line metabolically challenged by culture without glutamine (SUM149-MA cells), MO-I-500 inhibits cell proliferation. MO-I-500 also displays anticonvulsant activity in a 6 Hz mouse model of epilepsy at nontoxic doses.

product keywords :

FTO inhibitors inhibits anticonvulsant mRNA N6-methyladenine demethylase alfa alpha-ketoglutarate-dependent dioxygenase fat mass and obesity-associated protein Other Oxygenases/Oxidases 6871,

extended description :

FTO inhibitor; anticonvulsant

chemical name text :

N-[5-(4-Chlorophenyl)-3,4-dihydroxy-2-furanyl]ethanesulfonamide

formula :

C12H12ClNO5S

formula text :

C12H12ClNO5S

cas num :

1585219-04-0

USD :

235

USD 2025 :

212 USD

product details :

FTO inhibitor; anticonvulsant

more info or order :

Tocris Bioscience product webpage