uPSEM 817 tartrate | Tocris Bioscience 6866 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

uPSEM 817 tartrate

catalog :

6866

quantity :

25 mg

price :

764 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6866

SKU :

6866/25

product name :

uPSEM 817 tartrate

description :

Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant

target :

Pharmacologically Selective Effector Molecules/PSEM

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

419.43

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective ultrapotent PSEM (uPSEM) agonist for 7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channels (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).

catalog number base :

6866

product keywords :

uPSEM817 tartrate highly potent selective alpha7L131G,Q139L,Y217F-GlyR PSAM4-GlyR agonists agonism PSEM chemogenetics PSEMs Glycine Receptors 5-HT3 Receptors 6866, Chemogenetics, Pharmacologically Selective Effector Molecules, PSAM Agonist, Pharmacologically Selective Actuator Module Agonists, PSEM, PSEMs

extended description :

Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant

chemical name text :

2-Propoxy-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate

formula :

C 16 H 19 N 3 O.C 4 H 6 O 6

formula text :

C16H19N3O.C4H6O6

cas num :

2341833-14-3

2020 USD :

727

2021 USD :

764 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage