Ticagrelor | Tocris Bioscience 6864 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ticagrelor

catalog :

6864

quantity :

10 mg (also 50 mg)

price :

41 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Li L, Yang J, Liu B, Zou Y, Sun M, Li Z, et al. P2Y12 shRNA normalizes inflammatory dysfunctional hepatic glucokinase activity in type 2 diabetic rats. Biomed Pharmacother. 2020;132:110803 pubmed publisher

product information

brand :

Tocris

master code :

6864

SKU :

6864/10

product name :

Ticagrelor

description :

High affinity and reversible P2Y12 antagonist; displays inverse agonism in vitro; also inhibits ENT1

target :

P2Y Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

522.57

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity and reversible P2Y12 antagonist (pKi = 8.7) that displays inverse agonism in 1321N1 cells. Also high affinity inhibitor of equilibrative nucleoside transporter 1 (ENT1; Ki = 41 nM). Inhibits ADP-induced platelet aggregation.

catalog number base :

6864

product keywords :

high affinity purinergic P2Y12 receptor antagonists inverse agonists antagonism agonism ENT1 inhibitors inhibits equilibrative nucleoside transporter Purinergic P2Y Receptors Nucleoside Transporters 6864,

extended description :

High affinity and reversible P2Y12 antagonist; displays inverse agonism in vitro; also inhibits ENT1

chemical name text :

(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol

formula :

C 23 H 28 F 2 N 6 O 4 S

formula text :

C23H28F2N6O4S

cas num :

274693-27-5

2020 USD :

2021 USD :

41 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage