Anle138b | Tocris Bioscience 6861 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Anle138b

catalog :

6861

quantity :

25 mg

price :

309 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6861

SKU :

6861/25

product name :

Anle138b

description :

Oligomeric aggregation inhibitor; inhibits prion protein and -synuclein aggregate formation

target :

Neuronal Metabolism Peptides and Compounds

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

343.18

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Oligomeric aggregation inhibitor. Inhibits formation of pathological prion protein (PrPSc) and -synuclein aggregates in vitro . Prevents accumulation of PrPSc in brain and spleen, and prolongs survival of prion-infected mice. Exhibits neuroprotective effects in a Parkinson s disease mouse model and improves motor performance in an -synucleinopathy model. Orally bioavailable and brain penetrant.

catalog number base :

6861

product keywords :

oligomeric aggregation inhibitors inhibits prions PrPSc alpha alfa synuclein synucleinopathies brain penetrant Parkinson's disease Prion Protein 6861,

extended description :

Oligomeric aggregation inhibitor; inhibits prion protein and -synuclein aggregate formation

chemical name text :

3-(1,3-Benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole

formula :

C 16 H 11 BrN 2 O 2

formula text :

C16H11BrN2O2

cas num :

882697-00-9

2020 USD :

309

2021 USD :

309 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage