Anle138b | Tocris Bioscience 6861/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Anle138b

catalog :

6861/5

quantity :

5 mg (also 25 mg)

price :

100 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6861 - Anle138b C16H11BrN2O2 CAS No. 882697-00-9

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6861

SKU :

6861/5

product name :

Anle138b

description :

Oligomeric aggregation inhibitor; inhibits prion protein and -synuclein aggregate formation

target :

Neuronal Metabolism Peptides and Compounds

unit size :

5 mg (also 25 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

343.18

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Anle138b is an oligomeric aggregation inhibitor that inhibits formation of pathological prion protein (PrPSc) and -synuclein aggregates in vitro . Anle138b prevents accumulation of PrPSc in brain and spleen, and prolongs survival of prion-infected mice. Anle138b exhibits neuroprotective effects in a Parkinson s disease mouse model and improves motor performance in an -synucleinopathy model. Orally bioavailable and brain penetrant.

product keywords :

oligomeric aggregation inhibitors inhibits prions PrPSc alpha alfa synuclein synucleinopathies brain penetrant Parkinson's disease parkinsons neuroprotective Prion Protein 6861,

extended description :

Oligomeric aggregation inhibitor; inhibits prion protein and -synuclein aggregate formation

chemical name text :

3-(1,3-Benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole

formula :

C16H11BrN2O2

formula text :

C16H11BrN2O2

cas num :

882697-00-9

USD :

USD 2025 :

100 USD

product details :

Oligomeric aggregation inhibitor; inhibits prion protein and -synuclein aggregate formation

more info or order :

Tocris Bioscience product webpage