SB 290157 trifluoroacetate | Tocris Bioscience 6860 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 290157 trifluoroacetate

catalog :

6860

quantity :

5 mg

price :

75 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6860 - SB 290157 trifluoroacetate C22H28N4O4.CF3CO2H CAS No. 1140525-25-2

product information

brand :

Tocris

master code :

6860

SKU :

6860/5

product name :

SB 290157 trifluoroacetate

description :

Potent C3a receptor antagonist

target :

Complement Signaling inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

97%

observed molecular weight :

526.51

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent C3a receptor antagonist (IC50 values are 27 - 30 nM for C3a-induced Ca2+ mobilization in vitro and ex vivo ). Inhibits C3a-induced chemotaxis in human mast cell line. Also inhibits tau hyperphosphorylation in vitro . Displays anti-inflammatory effects in animal models of airway inflammation and arthritis. Also inhibits glucose-induced insulin secretion and ATP production from ex vivo human and mouse pancreatic islets. Also exhibits C3a receptor agonist activity.

catalog number base :

6860

product keywords :

SB290157 trifluoroacetate complement system receptor C3a antagonists antagonism antiinflammatory chemotaxis Complement 6860,

extended description :

Potent C3a receptor antagonist

chemical name text :

N2-[2-(2,2-Diphenylethoxy)acetyl]-L-arginine trifluoroacetate

formula :

C 22 H 28 N 4 O 4 .CF 3 CO 2 H

formula text :

C22H28N4O4.CF3CO2H

cas num :

1140525-25-2

2020 USD :

2021 USD :

75 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage