SB 290157 trifluoroacetate | Tocris Bioscience 6860/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 290157 trifluoroacetate

catalog :

6860/5

quantity :

5 mg

price :

88 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6860 - SB 290157 trifluoroacetate C22H28N4O4.CF3CO2H CAS No. 1140525-25-2

product information

brand :

Tocris

master code :

6860

SKU :

6860/5

rank :

0.06

product name :

SB 290157 trifluoroacetate

description :

Potent C3a receptor antagonist

target :

Complement Signaling inhibitors

category :

Small Molecules

sizes available :

5 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SB 290157 trifluoroacetate is a potent C3a receptor antagonist (IC50 values are 27 - 30 nM for C3a-induced Ca2+ mobilization in vitro and ex vivo ). Inhibits C3a-induced chemotaxis in human mast cell line. Also inhibits tau hyperphosphorylation in vitro . Displays anti-inflammatory effects in animal models of airway inflammation and arthritis. Also inhibits glucose-induced insulin secretion and ATP production from ex vivo human and mouse pancreatic islets. Also exhibits C3a receptor agonist activity.

extended description :

Potent C3a receptor antagonist

chemical name text :

N2-[2-(2,2-Diphenylethoxy)acetyl]-L-arginine trifluoroacetate

formula :

C 22 H 28 N 4 O 4 .CF 3 CO 2 H

formula text :

C22H28N4O4.CF3CO2H

cas num :

1140525-25-2

USD :

88 USD

product details :

Potent C3a receptor antagonist

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage