FITM | Tocris Bioscience 6859/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FITM

catalog :

6859/10

quantity :

10 mg (also 50 mg)

price :

162 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6859 - FITM C18H18FN5OS CAS No. 932737-65-0

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6859

SKU :

6859/10

product name :

FITM

description :

Potent and selective negative allosteric modulator of mGlu1 receptors

target :

Group I mGluR Modulators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

371.43

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

FITM is a potent and selective negative allosteric modulator of mGlu1 receptors (IC50 = 5.1 nM). Displays 1300-fold selectivity for mGlu1 over other metabotropic glutamate receptors (IC50 values are 7 M and 10 M for mGlu5 and mGlu2 or mGlu8, respectively). Antagonizes methamphetamine-induced locomotion in mice.

product keywords :

potent selective negative allosteric modulator antagonist mGlu1 group I metabotropic glutamate receptor Glutamate (Metabotropic) Group I Receptors 6859,

extended description :

Potent and selective negative allosteric modulator of mGlu1 receptors

chemical name text :

4-Fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide

formula :

C18H18FN5OS

formula text :

C18H18FN5OS

cas num :

932737-65-0

USD :

180

USD 2025 :

162 USD

product details :

Potent and selective negative allosteric modulator of mGlu1 receptors

more info or order :

Tocris Bioscience product webpage